San Francisco 49ers begin their 2021-22 NFL football season against the Detroit Lions in Week 1 on Sunday, September 12 at Ford Field, Detroit, MI, and expected to end their regular-season game against the Los Angeles Rams on Sunday, January 9, 2022, at SoFi Stadium, Inglewood, CA.
Here is the San Francisco 49ers’ schedule for upcoming games, time, date, location, TV channel, and results you need to know.
|Regular season||Opponent||Date||Time (ET)||Location||TV Channel||Results|
|Week 1||Lions||Sun., Sep. 12||1:00 pm||Ford Field, Detroit, MI||FOX|
|Week 2||Eagles||Sun., Sep. 19||1:00 pm||Lincoln Financial Field, Philadelphia, PA||FOX|
|Week 3||Packers||Sun., Sep. 26||8:20 pm||Levi’s Stadium, Santa Clara, CA||NBC|
|Week 4||Seahawks||Sun., Oct. 3||4:05 pm||Levi’s Stadium, Santa Clara, CA||FOX|
|Week 5||Cardinals||Sun., Oct. 10||4:25 pm||State Farm Stadium, Glendale, AZ||FOX|
|Week 7||Colts||Sun., Oct. 24||8:20 pm||Levi’s Stadium, Santa Clara, CA||NBC|
|Week 8||Bears||Sun., Oct. 31||1:00 pm||Soldier Field, Chicago, IL||FOX|
|Week 9||Cardinals||Sun., Nov. 7||4:25 pm||Levi’s Stadium, Santa Clara, CA||FOX|
|Week 10||Rams||Mon., Nov. 15||8:15 pm||Levi’s Stadium, Santa Clara, CA||ESPN|