The 2022 NFL Week 16 game will kick off on Thursday, December 22 with a game where the New York Jets will host the Jacksonville Jaguars at 8:15 p.m. ET for Thursday football live on Prime Video, and Week 16 football will be ended with a Monday football game where the Los Angeles Chargers will be the road to Indianapolis Colts on Monday, December 27 at 8:15 pm ET live on ESPN.
When is Thursday night football of NFL Week 16 in 2022?
The upcoming Thursday night football will take place on Thursday, December 22, 2022, at MetLife Stadium, East Rutherford between the Jacksonville Jaguars vs New York Jets tip-off set for 8:15 p.m. ET live on the NFLN network.
When is Sunday night football of NFL Week 16 in 2022?
The Tampa Bay Buccaneers will face the Arizona Cardinals for Sunday night football on Sunday, December 25, 2022, at State Farm Stadium, Glendale, AZ live on NBC at 8:20 p.m. ET.
When is Monday night football of NFL Week 16 in 2022?
The Los Angeles Chargers vs Indianapolis Colts is fixed for the 2022 Monday night football game at NFL Week 16 on Monday, December 26 at Lucas Oil Stadium, Indianapolis, IN live on ESPN starting at 8:15 p.m. ET.
Thursday, December 22
| Matchup | Time (ET) | TV | Arena Location |
| Jaguars @ Jets | 8:15 PM | Prime Video | MetLife Stadium, East Rutherford |
Saturday, December 24
| Matchup | Time (ET) | TV | Arena Location |
| Bills @ Bears | 1:00 PM | CBS | Soldier Field, Chicago |
| Saints @ Browns | 1:00 PM | CBS | FirstEnergy Stadium, Cleveland |
| Texans @ Titans | 1:00 PM | CBS | Nissan Stadium, Nashville |
| Seahawks @ Chiefs | 1:00 PM | FOX | GEHA Field at Arrowhead Stadium, Kansas City |
| Giants @ Vikings | 1:00 PM | FOX | U.S. Bank Stadium, Minneapolis |
| Bengals @ Patriots | 1:00 PM | CBS | Gillette Stadium, Foxboro |
| Lions @ Panthers | 1:00 PM | FOX | Bank of America Stadium, Charlotte |
| Falcons @ Ravens | 1:00 PM | FOX | M&T Bank Stadium, Baltimore |
| Commanders @ 49ers | 4:05 PM | CBS | Levi’s Stadium, Santa Clara |
| Eagles @ Cowboys | 4:25 PM | FOX | AT&T Stadium, Arlington |
| Raiders @ Steelers | 8:15 PM | NFLN | Heinz Field, Pittsburgh |
Sunday, December 25
| Matchup | Time (ET) | TV | Arena Location |
| Packers @ Dolphins | 1:00 PM | FOX | Hard Rock Stadium, Miami Gardens |
| Broncos @ Rams | 4:30 PM | CBS | SoFi Stadium, Inglewood |
| Buccaneers @ Cardinals | 8:20 PM | NBC | State Farm Stadium, Glendale |
Monday, December 26
| Matchup | Time (ET) | TV | Arena Location |
| Chargers @ Colts | 8:15 PM | ESPN | Lucas Oil Stadium, Indianapolis |