Chicago Bears vs Buffalo Bills Results
The Buffalo Bills and Chicago Bears played each other in the regular season and playoffs 12 times in league history. Buffalo Bills 6 games and Chicago Bears won 8 games in their all-time meeting here listed below.
Chicago Bears leading the all-time series 8-6-0
| Where | When | Results |
| Buffalo Bills at Chicago Bears | 12/24/2022 | 35-13 (Bills) |
| Chicago Bears at Buffalo Bills | 11/04/2018 | 41-9 (Bears) |
| Buffalo Bills at Chicago Bears | 09/07/2014 | 23-20 (Bills) |
| Chicago Bears at Buffalo Bills | 11/07/2010 | 22-19 (Bears) |
| Buffalo Bills at Chicago Bears | 10/08/2006 | 7-40 (Bears) |
| Chicago Bears at Buffalo Bills | 09/29/2002 | 27-33 (Bills) |
| Chicago Bears at Buffalo Bills | 11/12/2000 | 3-20 (Bills) |
| Buffalo Bills at Chicago Bears | 12/07/1997 | 3-20 (Bears) |
| Buffalo Bills at Chicago Bears | 10/02/1994 | 13-20 (Bears) |
| Chicago Bears at Buffalo Bills | 09/29/1991 | 20-35 (Bills) |
| Buffalo Bills at Chicago Bears | 10/02/1988 | 3-24 (Bears) |
| Chicago Bears at Buffalo Bills | 10/07/1979 | 7-0 (Bears) |
| Chicago Bears at Buffalo Bills | 10/27/1974 | 6-16 (Bills) |
| Buffalo Bills at Chicago Bears | 11/22/1970 | 13-31 (Bears) |