Carolina Panthers vs Buffalo Bills Results
The Buffalo Bills and Carolina Panthers played each other in the regular season and playoffs 8 times in league history. Buffalo Bills 6 games and Carolina Panthers won 2 games in their all-time meeting here listed below.
Buffalo Bills leading the all-time series 6-2-0.
| Where | When | Results |
| Carolina Panthers at Buffalo Bills | 12/19/2021 | 14-31 (Bills) |
| Buffalo Bills at Carolina Panthers | 09/17/2017 | 3-9 (Panthers) |
| Carolina Panthers at Buffalo Bills | 09/15/2013 | 23-24 (Bills) |
| Buffalo Bills at Carolina Panthers | 10/25/2009 | 20-9 (Bills) |
| Carolina Panthers at Buffalo Bills | 11/27/2005 | 13-9 (Panthers) |
| Carolina Panthers at Buffalo Bills | 12/09/2001 | 24-25 (Bills) |
| Buffalo Bills at Carolina Panthers | 10/25/1998 | 30-14 (Bills) |
| Carolina Panthers at Buffalo Bills | 09/10/1995 | 9-31 (Bills) |