Tampa Bay Buccaneers vs San Francisco 49ers Results
The Tampa Bay Buccaneers and San Francisco 49ers played each other in the regular season and playoffs 26 times in league history. Tampa Bay Buccaneers 7 games and the San Francisco 49ers won 19 games in their all-time meeting here listed below.
San Francisco 49ers leading the all-time series 19-7-0
| When | Where | Results |
| 12/11/2022 | Tampa Bay Buccaneers at San Francisco 49ers | 35-7 (49ers) |
| 09/08/2019 | San Francisco 49ers at Tampa Bay Buccaneers | 31-17 (49ers) |
| 11/25/2018 | San Francisco 49ers at Tampa Bay Buccaneers | 9-27 (Buccaneers) |
| 10/23/2016 | Tampa Bay Buccaneers at San Francisco 49ers | 34-17 (Buccaneers) |
| 12/15/2013 | San Francisco 49ers at Tampa Bay Buccaneers | 33-14 (49ers) |
| 10/09/2011 | Tampa Bay Buccaneers at San Francisco 49ers | 3-48 (49ers) |
| 11/21/2010 | Tampa Bay Buccaneers at San Francisco 49ers | 21-0 (Buccaneers) |
| 12/23/2007 | Tampa Bay Buccaneers at San Francisco 49ers | 19-21 (49ers) |
| 10/30/2005 | Tampa Bay Buccaneers at San Francisco 49ers | 10-15 (49ers) |
| 11/21/2004 | San Francisco 49ers at Tampa Bay Buccaneers | 3-35 (Buccaneers) |
| 10/19/2003 | Tampa Bay Buccaneers at San Francisco 49ers | 7-24 (49ers) |
| 01/12/2003 | San Francisco 49ers at Tampa Bay Buccaneers | 6-31 (Buccaneers) |
| 08/31/1997 | San Francisco 49ers at Tampa Bay Buccaneers | 6-13 (Buccaneers) |
| 10/23/1994 | Tampa Bay Buccaneers at San Francisco 49ers | 16-41 (49ers) |
| 11/14/1993 | San Francisco 49ers at Tampa Bay Buccaneers | 45-21 (49ers) |
| 12/19/1992 | Tampa Bay Buccaneers at San Francisco 49ers | 14-21 (49ers) |
| 11/18/1990 | Tampa Bay Buccaneers at San Francisco 49ers | 7-31 (49ers) |
| 09/17/1989 | San Francisco 49ers at Tampa Bay Buccaneers | 20-16 (49ers) |
| 11/22/1987 | San Francisco 49ers at Tampa Bay Buccaneers | 24-10 (49ers) |
| 09/07/1986 | San Francisco 49ers at Tampa Bay Buccaneers | 31-7 (49ers) |
| 11/18/1984 | Tampa Bay Buccaneers at San Francisco 49ers | 17-24 (49ers) |
| 12/04/1983 | Tampa Bay Buccaneers at San Francisco 49ers | 21-35 (49ers) |
| 10/26/1980 | Tampa Bay Buccaneers at San Francisco 49ers | 24-23 (Buccaneers) |
| 12/09/1979 | Tampa Bay Buccaneers at San Francisco 49ers | 7-23 (49ers) |
| 12/10/1978 | Tampa Bay Buccaneers at San Francisco 49ers | 3-6 (49ers) |
| 10/30/1977 | Tampa Bay Buccaneers at San Francisco 49ers | 10-20 (49ers) |