2021 NFL Week 5 Schedule, Time, TV Channel
The 2021 NFL Week 5 game will kick off on Thursday, October 7 the Seattle Seahawks hosting the LA Rams at 8:20 pm ET on NFLN, and in the Sunday Night Football between Buffalo Bills will visit Kansas City Chiefs at 8:20 pm ET on NBC, and Week 5 will conclude with Indianapolis Colts visit Baltimore Ravens Monday, October 11 at 8:15 pm ET on ESPN.
NFL Week 5 – Thursday, October 7
| Team | Time (ET) | TV Channel |
| LA Rams at Seattle | 8:20 pm | FOX/NFLN/AMAZON |
Sunday, October 10
| Team | Time (ET) | TV Channel |
| NY Jets at Atlanta | 9:30 am | NFLN |
| Philadelphia at Carolina | 1:00 pm | FOX |
| Green Bay at Cincinnati | 1:00 pm | FOX |
| New England at Houston | 1:00 pm | CBS |
| Tennessee at Jacksonville | 1:00 pm | CBS |
| Detroit at Minnesota | 1:00 pm | FOX |
| Denver at Pittsburgh | 1:00 pm | FOX |
| Miami at Tampa Bay | 1:00 pm | CBS |
| New Orleans at Washington | 1:00 pm | CBS |
| Cleveland at LA Chargers | 4:05 pm | CBS |
| Chicago at Las Vegas | 4:05 pm | CBS |
| San Francisco at Arizona | 4:25 pm | FOX |
| NY Giants at Dallas | 4:25 pm | FOX |
| Buffalo at Kansas City | 8:20 pm | NBC |
| Team | Time (ET) | TV Channel |
| Indianapolis at Baltimore | 8:15 pm | ESPN |