2022 NFL Week 5 Schedule, Time, TV Channel
The 2022 NFL Week 5 game will kick off on Thursday, October 6 where the Denver Broncos hosting the Indianapolis Colts at 8:20 pm ET on NFLN, and the Sunday Night Football between Cincinnatti Bengals will visit Baltimore Ravens at 8:20 pm ET on October 9 live on NBC, and Week 5 will conclude with Las Vegas Raiders will visit Kansas City Chiefs on Monday, October 11 at 8:15 pm ET on ESPN.
Thursday, October 6
| Matchup | Time (ET) | TV | Arena Location |
| Colts @ Broncos | 8:20 PM | Prime Video | Empower Field at Mile High, Denver |
Sunday, October 9
| Matchup | Time (ET) | TV | Arena Location |
| Giants @ Packers | 9:30 AM | NFLN | Tottenham Hotspur Stadium, London |
| Steelers @ Bills | 1:00 PM | CBS | Highmark Stadium, Orchard Park |
| Chargers @ Browns | 1:00 PM | CBS | FirstEnergy Stadium, Cleveland |
| Bears @ Vikings | 1:00 PM | FOX | U.S. Bank Stadium, Minneapolis |
| Lions @ Patriots | 1:00 PM | FOX | Gillette Stadium, Foxboro |
| Seahawks @ Saints | 1:00 PM | FOX | Caesars Superdome, New Orleans |
| Dolphins @ Jets | 1:00 PM | CBS | MetLife Stadium, East Rutherford |
| Falcons @ Buccaneers | 1:00 PM | FOX | Raymond James Stadium, Tampa |
| Titans @ Commanders | 1:00 PM | CBS | FedExField, Landover |
| Texans @ Jaguars | 1:00 PM | CBS | TIAA Bank Field, Jacksonville |
| 49ers @ Panthers | 4:05 PM | CBS | Bank of America Stadium, Charlotte |
| Cowboys @ Rams | 4:25 PM | FOX | SoFi Stadium, Inglewood |
| Eagles @ Cardinals | 4:25 PM | FOX | State Farm Stadium, Glendale |
| Bengals @ Ravens | 8:20 PM | NBC | M&T Bank Stadium, Baltimore |
Monday, October 10
| Matchup | Time (ET) | TV | Arena Location |
| Raiders @ Chiefs | 8:15 PM | ESPN | GEHA Field at Arrowhead Stadium, Kansas City |