New Orleans Saints vs Buffalo Bills Results
The New Orleans Saints and Buffalo Bills played each other in the regular season and playoffs 12 times in league history. New Orleans Saints win 7 games and Buffalo Bills won 5 games in their all-time meeting here listed below.
New Orleans Saints leading the all-time series 7-5-0.
| When | Where | Results |
| 11/25/2021 | Buffalo Bills at New Orleans Saints | 31-6 (Bills) |
| 11/12/2017 | New Orleans Saints at Buffalo Bills | 47-10 (Saints) |
| 10/27/2013 | Buffalo Bills at New Orleans Saints | 17-35 (Saints) |
| 09/27/2009 | New Orleans Saints at Buffalo Bills | 27-7 (Saints) |
| 10/02/2005 | Buffalo Bills at New Orleans Saints | 7-19 (Saints) |
| 09/09/2001 | New Orleans Saints at Buffalo Bills | 24-6 (Saints) |
| 12/27/1998 | Buffalo Bills at New Orleans Saints | 45-33 (Bills) |
| 12/20/1992 | Buffalo Bills at New Orleans Saints | 20-16 (Bills) |
| 12/10/1989 | New Orleans Saints at Buffalo Bills | 22-19 (Saints) |
| 10/30/1983 | New Orleans Saints at Buffalo Bills | 21-27 (Bills) |
| 09/21/1980 | Buffalo Bills at New Orleans Saints | 35-26 (Bills) |
| 11/04/1973 | Buffalo Bills at New Orleans Saints | 0-13 (Saints) |