Buffalo Bills vs Los Angeles Chargers Results
The Buffalo Bills and Los Angeles Chargers played each other in the regular season and playoffs 41 times in league history. Buffalo Bills 14 games and Los Angeles Chargers won 25 games in their all-time meeting here listed below.
Los Angeles Chargers leading the all-time series 25-14-2.
| Where | When | Results |
| Buffalo Bills at Los Angeles Chargers | 12/23/2023 | 24-22 (Bills) |
| Los Angeles Chargers at Buffalo Bills | 11/29/2020 | 17-27 (Bills) |
| Los Angeles Chargers at Buffalo Bills | 09/16/2018 | 31-20 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 11/19/2017 | 24-54 (Chargers) |
| San Diego Chargers at Buffalo Bills | 09/21/2014 | 22-10 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 12/11/2011 | 10-37 (Chargers) |
| San Diego Chargers at Buffalo Bills | 10/19/2008 | 14-23 (Bills) |
| San Diego Chargers at Buffalo Bills | 12/03/2006 | 24-21 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 11/20/2005 | 10-48 (Chargers) |
| San Diego Chargers at Buffalo Bills | 12/15/2002 | 13-20 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 10/28/2001 | 24-27 (Chargers) |
| San Diego Chargers at Buffalo Bills | 10/15/2000 | 24-27 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 09/06/1998 | 14-16 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 12/01/1985 | 7-40 (Chargers) |
| San Diego Chargers at Buffalo Bills | 09/08/1985 | 14-9 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 12/06/1981 | 28-27 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 01/03/1981 | 14-20 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 10/05/1980 | 26-24 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 09/16/1979 | 19-27 (Chargers) |
| San Diego Chargers at Buffalo Bills | 11/21/1976 | 34-13 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 09/23/1973 | 7-34 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 10/23/1971 | 3-20 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 12/14/1969 | 6-45 (Chargers) |
| San Diego Chargers at Buffalo Bills | 11/17/1968 | 21-6 (Chargers) |
| San Diego Chargers at Buffalo Bills | 10/01/1967 | 37-17 (Chargers) |
| San Diego Chargers at Buffalo Bills | 10/16/1966 | 17-17 (Tie) |
| Buffalo Bills at Los Angeles Chargers | 09/04/1966 | 7-27 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 12/26/1965 | 23-0 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 11/25/1965 | 20-20 (Tie) |
| San Diego Chargers at Buffalo Bills | 10/10/1965 | 34-3 (Chargers) |
| San Diego Chargers at Buffalo Bills | 12/26/1964 | 7-20 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 11/26/1964 | 27-24 (Bills) |
| San Diego Chargers at Buffalo Bills | 09/26/1964 | 3-30 (Bills) |
| San Diego Chargers at Buffalo Bills | 11/17/1963 | 23-13 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 09/08/1963 | 10-14 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 11/11/1962 | 40-20 (Bills) |
| San Diego Chargers at Buffalo Bills | 10/13/1962 | 10-35 (Bills) |
| Buffalo Bills at Los Angeles Chargers | 12/10/1961 | 10-28 (Chargers) |
| San Diego Chargers at Buffalo Bills | 09/30/1961 | 19-11 (Chargers) |
| Buffalo Bills at Los Angeles Chargers | 11/20/1960 | 32-3 (Bills) |
| San Diego Chargers at Buffalo Bills | 10/02/1960 | 24-10 (Chargers) |