Buffalo Bills vs Arizona Cardinals Results
The Buffalo Bills and Arizona Cardinals played each other in the regular season and playoffs 12 times in league history. Buffalo Bills 7 games and Arizona Cardinals won 5 games in their all-time meeting here listed below.
Buffalo Bills leading the all-time series 7-5-0.
| Where | When | Results |
| Buffalo Bills at Arizona Cardinals | 11/15/2020 | 30-32 (Cardinals) |
| Arizona Cardinals at Buffalo Bills | 09/25/2016 | 18-33 (Bills) |
| Buffalo Bills at Arizona Cardinals | 10/14/2012 | 19-16 (Bills) |
| Buffalo Bills at Arizona Cardinals | 10/05/2008 | 17-41 (Cardinals) |
| Arizona Cardinals at Buffalo Bills | 10/31/2004 | 14-38 (Bills) |
| Buffalo Bills at Arizona Cardinals | 12/19/1999 | 31-21 (Bills) |
| Phoenix Cardinals at Buffalo Bills | 11/11/1990 | 14-45 (Bills) |
| St. Louis Cardinals at Buffalo Bills | 09/21/1986 | 10-17 (Bills) |
| Buffalo Bills at St. Louis Cardinals | 09/09/1984 | 7-37 (Cardinals) |
| Buffalo Bills at St. Louis Cardinals | 11/15/1981 | 0-24 (Cardinals) |
| Buffalo Bills at St. Louis Cardinals | 11/27/1975 | 32-14 (Bills) |
| St. Louis Cardinals at Buffalo Bills | 10/31/1971 | 28-23 (Cardinals) |